Publications

Activity of PF-1 and PF-2, Novel Siderophore Conjugated Beta-lactams, Tested Against Enterobacteriaceae Strains Carrying Emerging Resistance Mechanisms, Lead author: Farrell DJ, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Antimicrobial Activity and Spectrum of Doripenem against Contemporary (2010) Clinical Bacterial Pathogens from Europe, Lead author: Farrell DJ, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Linezolid Susceptibility in Europe for 2010: ZAAPS Program (5,532 strains), Lead author: Jones RN, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Ribosomal mutations associated with ketolide resistance in Haemophilus influenzae found in the SENTRY Antimicrobial Surveillance Program, Lead author: Farrell DJ, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Activity of Ceftaroline and Comparator Agents Tested Against Organisms Responsible for Community-Acquired Respiratory Tract Infections in Europe (2009), Lead author: Sader HS, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Association of 16S rRNA Methylases and NDM-1 in Isolates from Indian Hospitals Collected in 2006-2007, Lead author: Castanheira M, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

IMP-18-Producing Klebsiella oxytoca, Increasing Genetic Diversity of Metallo-beta-Lactamases in Mexican Hospitals, Lead author: Castanheira M, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Genotypic Evaluation of a Collection of Cfr-producing Staphylococcal Clinical Isolates from the SENTRY Antimicrobial Surveillance Program., Lead author: Mendes RE, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

NDM-1 in Israel, Evidence of Traveling and Carriage of Carbapenem-Resistant Organisms, Lead author: Castanheira M, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Evaluation of quinolone resistance determining region mutations and efflux pump expression in Neisseria meningitidis resistant to fluoroquinolones, Lead author: Castanheira M, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

EUCAST MIC breakpoints and inhibition zone diameter correlates for staphylococci, Lead author: Matuschek, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Antimicrobial Susceptibility of Enterococci and Streptococci from United States (USA) Hospitals: A 9-Year Summary of the Daptomycin Surveillance Program (2002-2010), Lead author: Sader HS, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Antimicrobial activity and spectrum of daptomycin tested against Gram-positive strains collected in European hospitals: Results from 7 years of surveillance (2003-2009), Lead author: Sader HS, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Fusidic Acid Activity and Coverage of Gram-positive Pathogens Associated with Acute Bacterial Skin and Skin Structure Infections (ABSSSI) in the USA (2008-2010), Lead author: Jones RN, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Antimicrobial Activity of Ceftaroline Tested Against Common Pathogens Causing Complicated Skin and Soft Tissue Infections in European Medical Centres in 2009, Lead author: Sader HS, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Comprehensive analysis of telavancin activity against staphylococcal isolates from Europe (2009-2010), including strains with reduced susceptibility to vancomycin, Lead author: Mendes RE, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Evaluation of L6 ribosomal protein alterations in fusidic acid-resistant Staphylococcus aureus: fitness cost and time-kill analysis, Lead author: Castanheira M, presented at 21st annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May 7 – 10, 2011, Milan, Italy

Pre-clinical development of antifungal susceptibility test methods for the testing of the novel antifungal agent E1210 versus Candida: Comparison of CLSI and EUCAST methods. by Pfaller MA, Watanabe N, Castanheira M, Messer SA and Jones RN published in J. Antimicrob. Chemother. 2011; 66 (11): 2581-2584

In vitro activity of a novel broad-spectrum antifungal, E1210, and comparators against Aspergillus spp. as determined by CLSI and EUCAST broth microdilution methods. by Pfaller MA, Castanheira M, Messer SA and Jones RN published in Antimicrob. Agents Chemother. 2011; 55 (11): 5155-5158

Comparative effects of carbapenems on bacterial load and host immune response in a Klebsiella pneumoniae murine pneumonia model. by Hilliard JJ, Melton JL, Hall L, Abbanat D, Fernandez J, Ward CK, Bunting RA, Barron A, Lynch AS and Flamm RK published in Antimicrob. Agents Chemother. 2011; 55 (2): 836-844

Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: Results from the SENTRY Antimicrobial Surveillance Program (2006-2009) by Gales AC, Jones RN and Sader HS published in J. Antimicrob. Chemother. 2011; 66 (9): 2070-2074

Characterization of global patterns and the genetics of fusidic acid resistance. by Farrell DJ, Castanheira M and Chopra I published in Clin. Infect. Dis. 2011; 52 (Suppl 7): S487-S492

LEADER Program results for 2009: An activity and spectrum analysis of linezolid using 6,414 clinical isolates from the United States (56 medical centers). by Farrell DJ, Mendes RE, Ross JE, Sader HS and Jones RN published in Antimicrob. Agents Chemother. 2011; 55 (8): 3684-3690

Quality control guidelines for Amphotericin B, itraconazole, posaconazole and voriconazole disk diffusion susceptibility tests on non-supplemented Mueller-Hinton Agar (CLSI M51-A document) of nondermatophyte filamentous fungi by Espinel-Ingroff A, Canton E, Fothergill A, Ghannoum M, Johnson L, Jones RN, Ostrosky-Zeichner L, Schell W, Gibbs DL, Wang A and Turnidge J published in J. Clin. Microbiol. 2011; 49 (7): 2568-2571

Analytical and clinical validation of novel real-time reverse transcriptase-polymerase chain reaction assays for the clinical detection of swine-origin H1N1 influenza viruses. by Duncan C, Guthrie JL, Tijet N, Elgngihy N, Turenne C, Seah C, Lau R, McTaggart L, Mallo G, Perusini S, Rebbapragada A, Melano R, Low DE, Farrell D and Guyard C published in Diagn. Microbiol. Infect. Dis. 2011; 69 (2):167-171

Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. by Del Grosso M, Camilli R, Barbabella G, Blackman Northwood J, Farrell DJ and Pantosti A published in Antimicrob. Agents Chemother. 2011; 55 (7): 3226-3230

Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007-09. by Davies TA, Marie Queenan A, Morrow BJ, Shang W, Amsler K, He W, Lynch AS, Pillar C and Flamm RK published in J. Antimicrob. Chemother. 2011; 66 (10): 2298-2307

Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. by Allen VG, Farrell DJ, Rebbapragada A, Tan J, Tijet N, Perusini SJ, Towns L, Lo S, Low DE and Melano RG published in Antimicrob. Agents Chemother. 2011; 55 (2): 703-712

Wild-type MIC distributions and epidemiologic cutoff values for fluconazole, posaconazole, and voriconazole when testing Cryptococcus neoformans as determined by the CLSI broth microdilution method. by Pfaller MA, Castanheira M, Diekema DJ, Messer SA and Jones RN published in Diagn. Microbiol. Infect. Dis. 2011; 71 (3): 252-259

Plasmid-borne vga(A)-encoding gene in methicillin-resistant Staphylococcus aureus ST398 recovered from swine and a swine farmer in the United States. by Mendes RE, Smith TC, Deshpande L, Diekema DL, Sader HS and Jones RN published in Diagn. Microbiol. Infect. Dis.2011; 71 (2): 177-180

In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution method. by Pfaller MA, Hata K, Jones RN, Messer SA, Moet GJ and Castanheira M published in Diagn. Microbiol. Infect. Dis. 2011; 71 (2): 167-170

Definitions and epidemiology of Candida species not susceptible to echinocandins by Pfaller MA, Diekema DJ, Castanheira M and Jones RN published in Curr. Fungal Infect. Rep. 2011; 5: 120-127

Candida glabrata mutants demonstrating paradoxical reduced caspofungin susceptibility but increased micafungin susceptibility. by Healey KR, Katiyar SK, Castanheira M, Pfaller MA and Edlind TD published in Antimicrob. Agents Chemother. 2011; 55 (8): 3947-3949

Antimicrobial susceptibility of daptomycin and comparator agents tested against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci: trend analysis of a 6-year period in US medical centers (2005-2010). by Sader HS, Moet GJ, Farrell DJ and Jones RN published in Diagn. Microbiol. Infect. Dis 2011; 70 (3): 412-416

JNJ-Q2, a new fluoroquinolone with potent in vitro activity against Staphylococcus aureus, including methicillin- and fluoroquinolone-resistant strains. by Farrell DJ, Liverman LC, Biedenbach DJ, Jones RN published in Antimcrob. Agents Chemother. 2011; 55 (7): 3631-3634

Eight-year (2002-2009) summary of the linezolid (Zyvox Annual Appraisal of Potency and Spectrum; ZAAPS) program in European countries by Ross JE, Farrell DJ, Mendes RE, Sader HS, Jones RN published in J. Chem. 2011; 23 (2):71-76

Antimicrobial activty of CXA-101, a novel cephalosporin tested in combination with tazobactam against Enterobacteriaceae, Pseudomonas aeruginosa, and Bacteroides fragilis strains having various resistance phenotypes. by Sader HS, Rhomberg PR, Farrell DJ, Jones RN published in Antimicrob. Agents Chemother. 2011; 55 (5): 2390-2394

OXA-163, an OXA-48-related class D beta-lactamase with extended activity toward expanded spectrum cephalosporins. by Poirel L, Castanheira M, Carrer A, Rodrguez CP, Jones RN, Smayevsky J and Nordmann P published in Antimicrob. Agents Chemother. 2011; 55 (6): 2546-2551

Comparative activity of linezolid against respiratory tract infection isolates of Staphylococcus aureus: An 11 year report from the SENTRY Antimicrobial Surveillance Program. by Jones RN, Farrell DJ, Sader HS published in Int. J. Antimicrob. Agents 2011; 37 (6): 580-587

Molecular typing of antimicrobial-resistant Shiga-toxin-producing Escherichia coli strains (STEC) in Brazil. by Cergole-Novella MC, Pignatari ACC, Castanheira M and Guth BEC published in Res. Microbiol. 2011; 162 (2): 117-123

Trends in carbapenemase-producing Escherichia coli and Klebsiella spp. from Europe and the Americas: Report from the SENTRY Antimicrobial Surveillance Programme (2007-09). by Castanheira M, Mendes RE, Woosley LN and Jones RN published in J. Antimicrob. Chemother. 2011; 66 (6): 1409-1411

Tigecycline activity tested against multidrug-resistant Enterobacteriaceae and Acinetobacter spp. isolated in US medical centers. by Sader HS, Farrell DJ and Jones RN published in Diagn. Microbiol. Infect. Dis. 2011; 69 (2): 223-227

Susceptibility of Klebsiella spp. to colistin and polymyxin B: Results from the SENTRY Antimicrobial Surveillance Program (2006-2009). by Sader HS, Farrell DJ and Jones RN published in Int. J. Antimicrob. Agents. 2011; 37 (2): 174-175

Geographic variations in species distribution and echinocandin and azole antifungal resistance rates among Candida bloodstream infection isolates: Report from the SENTRY Antimicrobial Surveillance Program (2008 to 2009). by Pfaller MA, Moet GJ, Messer SA, Jones RN and Castanheira M published in J. Clin. Microbiol. 2011; 49 (1): 396-399

Echinocandin and triazole antifungal susceptibility profiles for Candida spp. Cryptococcus neoformans, and Aspergillus fumigatus: Application of new CLSI clinical breakpoints and epidemiologic cutoff values to characterize resistance in the SENTRY Antimicrobial Surveillance Program (2009). by Pfaller MA, Castanheira M, Messer SA, Moet GJ, Jones RN published in Diagn. Microbiol. Infect. Dis. 2011; 69 (1): 45-50

Results of the Canadian Ward Surveillance Study (CANWARD) (2007-2009), a journal symposium. by Jones RN published in Diagn. Microbiol. Infect. Dis. 2011; 69 (3): 288

John A. Washington, MD (1936-2010). by Jones RN published in Diagn. Microbiol. Infect. Dis. 2011; 69 (3): 239

Investigation of the potential for mutational resistsance to XF-73, retapamulin, mupirocin, fusidic acid, daptomycin, and vancomycin in methicillin-resistant Staphylococcus aureus isolates during a 55-passage study by Farrell DJ, Robbins M Rhys-Williams and Love WG published in Antimicrob. Agents Chemother. 2011; 55 (3): 1177-1181

In vitro activity of telavancin and comparator antimicrobial agents against a panel of genetically defined staphylococci. by Farrell DJ, Krause KM and Benton BM published in Diagn. Microbiol. Infect. Dis. 2011; 69 (3): 257-279

In vitro activity and single-step mutational analysis of rifamycin SV tested against enteropathogens associated with traveler’s diarrhea and Clostridium difficile. by Farrrell DJ, Putnam SD Biedenbach DJ, Moro L, Bozzella R, Celasco G and Jones RN published in Antimicrob. Agents Chemother. 2011; 55 (3): 992-996