Publications

Pharmacokinetic-Pharmacodynamic (PK-PD) Basis for CLSI Carbapenem (CARB) Susceptibility Breakpoint Changes, Lead author: Bhavnani SM, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Rare Occurrence of Retapamulin Resistance Mechanisms in Staphylococcus aureus Clinical Isolates: Report from the SENTRY Program, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

First Report of cfr-Carrying Staphylococcal Clinical Isolates in Mexico and Evidence of In Vivo cfr Mobilization, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Decreased-Linezolid Susceptibility Due to cfr in a Community-Associated Methicillin-Resistant Staphylococcus aureus (MRSA) Clone (USA300), Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Genetic Characterization and Comparative Antimicrobial Susceptibility of a New bla_VIM-Variant, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Oxa-163, an Oxa-48-Related Class D Beta-Lactamase with an Extended Activity to Expanded-Spectrum Cephalosporins, Lead author: Poirel, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Mechanisms of Resistance and Antimicrobial Susceptibility Profile of Carbapenem-Resistant Acinetobacter baumanii from P.R. China, Lead author: Wang, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Genetic Characterization of bla_KPC-2-Carrying Klebsiella pneumoniae Collected from P.R. China During the 2009 SENTRY Antimicrobial Surveillance Program, Lead author: Wang, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Reduced Susceptibility to Extended-Spectrum Cephalosporins (ESC^RS) in Neisseria gonorrhoeae from Ontario, Canada, Lead author: Melano, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Plasmid-Borne vga(A)-Encoding Gene in Methicillin-Resistant Staphylococcus aureus (MRSA) ST-398 from Swine and Swine Farmer in the United States, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

IS21-558 Insertion Sequences Associated with cfr Dissemination in S. epidermidis and S. aureus Recovered from two Medical Facilities in Ohio, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Extended-Spectrum β-Lactamases (ESBLs) and Serine Carbapenemases in Pseudomonas aeruginosa from the Asia-Pacific Region: Report from the SENTRY Surveillance Program, Lead author: Bell JM, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Emergence of GES-Type ESBLs in Pseudomonas aeruginosa in Indian Hospitals, Lead author: Bell JM, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Dissemination of NDM-1-producing Enterobacteriaceae in India, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Recent Antimicrobial Resistance Increases among S. pneumoniae in Four Geographic Regions: Report from the SENTRY Antimicrobial Surveillance Program, Lead author: Jones RN, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

GSK1322322 MIC Quality Control (QC) Ranges Using CLSI Multi-Laboratory M23-A3 Study Design, Lead author: Ross JE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Determination of Disk Diffusion and MIC Quality Control Ranges for BC-3781 using CLSI Multi-Laboratory M23-A3 Study Design, Lead author: Ross JE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

A Multi-Site Study Evaluating the 18-24h Sensititre Susceptibility System for Imipenem/EDTA Screen Test for Metallo-Beta-Lactamases (MBLs) with Enterobacteriaciae, Lead author: Holliday, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Carbapenemase Occurrences among E. coli and Klebsiella spp. from Europe and the Americas (2007 – 2009), Lead author: Castanheira M, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Updated Correlations between Susceptibility (S) Testing Results for Nalidixic Acid (NA) and Fluoroquinolones (FQ) When Testing Salmonella spp., Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Comprehensive In Vitro Assessment of Oritavancin Activity Tested against S. aureus Causing Invasive Disease (2008 – 2009), Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

In Vitro Evaluation of PTK 0796 Activity Tested against Staphylococcus aureus, Including Hospital- and Community-Associated MRSA Strains from the USA and Europe, Lead author: Biedenbach DJ, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Update on Telavancin Activity Tested against a Collection of Gram-Positive Pathogens from US Hospitals (2007-2009), Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Activity of Oritavancin Tested against Vancomycin-Resistant Enterococci Recovered from Bacteremic Patients in USA and European Hospitals (2008 – 2009), Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Tigecycline Activity Tested Against Rarely Recovered Gram-positive Species, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Antimicrobial Activity of PTK 0796 Tested against Gram-positive Organisms Causing Bloodstream Infections in 2009, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Activity of Ceftaroline/NXL104 Tested against Contemporary (2009) Clinical Isolates of Staphylococci and Streptococci Collected from USA Medical Centers, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Antimicrobial Activity of Ceftazidime/NXL104 Tested Against Gram-Negative Organisms, Including Multidrug-Resistant Subsets, Causing Infections in USA and European Medical Centers, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Antimicrobial Spectrum and Potency of Ceftaroline Combined With NXL104 When Tested Against Enterobacteriaceae Collected From USA Hospitals, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Worldwide Summary of Doripenem Spectrum and Activity: Potencies against 128,444 Gram-Positive Pathogens, Lead author: Farrell DJ, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Antimicrobial Activity of a Novel Polymyxin Analog (CB-182,804) Tested against Clinical Strains of Gram-Negative Bacilli, including Colistin-Resistant Organisms, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Potency and Spectrum of Activity of AN3365: A Novel Boron-Containing Protein Synthesis Inhibitor Tested against Enterobacteriaceae, Lead author: Mendes RE, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Potency and Spectrum of Activity of AN3365, a Novel Boron-containing Protein Synthesis Inhibitor, Tested against Non-fermentative Gram-negative Bacilli, Lead author: Biedenbach DJ, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Activity BC-3781, a Novel Pleuromutilin Compound, Tested against Clinical Isolates of MRSA, Including Molecularly Characterized Community-Acquired and Hospital-Associated Strains, Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Antimicrobial Activity of the Investigational Pleuromutilin BC-3781 against Organisms Responsible for Community-Acquired Respiratory Tract Infections (CA-RTI), Lead author: Sader HS, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

In Vitro Activity of MC-1: A New Gram-Negative Antimicrobial Agent, Lead author: Farrell DJ, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Quality Control (QC) Limits for Antifungal Disk Diffusion Susceptibility Testing of Filamentous Fungi (Moulds) to Itraconazole, Posaconazole, Voriconazole & Amphotericin B, Lead author: Espinel-Ingroff, presented at 50th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 12 – 15, 2010, Boston, MA

Activity of Ceftaroline/NXL104 and Comparator Agents Tested Against Enterobacteriaceae Strains Producing KPC Serine-Carbapenemases, Lead author: Castanheira M, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Fluoroquinolone-resistant (FQR) H. influenzae (HI) Continue to be Infrequently Isolated, Within Worldwide Surveillance Networks (1997-2008), Lead author: Biedenbach DJ, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Linezolid Experience and Accurate Determination of Resistance (LEADER) Program: United States (USA) Results for 2009, Lead author: Ross JE, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Prevalence and Antimicrobial Susceptibility Profile of ESBL- and KPC-producing Enterobacteriaceae in the United States (2003-2008), Lead author: Jones RN, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Assessment of NXL104 Disk Content to Be Used to Test Ceftaroline in Combination, Lead author: Sader HS, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Evaluation of the Effects of pH, Serum Protein Concentration, Media Supplements, Inoculum Size, Media Type, and Incubation Conditions on Activity of Ceftaroline Combined with NXL104, Lead author: Rhomberg PR, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

A Multi-Site Study of the Sensititre® Susceptibility System Compared with the CLSI Microdilution Method using New CLSI Breakpoints for MIC Determination of Enterobacteriaceae vs. Cephems, Lead author: Holliday, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Design and Evaluation of a Novel Dual-target Real-time PCR Assay for Neisseria gonorrhoeae Detection in Clinical Specimens, Lead author: Rebbapragada, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Telavancin Activity against Gram-positive Bacteria Isolated from Respiratory Tract Specimens of Patients with Nosocomial Pneumonia (2007-2008), Lead author: Mendes RE, presented at American Thoracic Society (ATS), May 14 – 19, 2010, New Orleans, LA

Ceftaroline Activity Against Bacterial Isolates from Patients with Community-Acquired Respiratory Tract Infections from United States Medical Centers in 2009, Including Methicillin-Resistant Staphylococcus aureus, Lead author: Sader HS, presented at American Thoracic Society (ATS), May 14 – 19, 2010, New Orleans, LA

Antimicrobial Activity and Spectrum of the Novel Cephalosporin Ceftaroline Tested Against Bacterial Isolates Causing Skin and Skin Structure Infections in USA Medical Centers, Lead author: Farrell DJ, presented at 30th annual Surgical Infection Society (SIS), April 17 – 20, 2010, Las Vegas, NV

Ceftaroline Activity against Clinical Isolates of Staphylococcus aureus, Including Methicillin-Resistant Strains (MRSA), from United States Hospitals, Lead author: Sader HS, presented at 30th annual Surgical Infection Society (SIS), April 17 – 20, 2010, Las Vegas, NV

Antimicrobial activity of tigecycline and comparator agents tested against clinical bacterial strains from the Asia-Pacific region, 2008-2009, Lead author: Jan Bell, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria