Publications

Fluoroquinolone-resistant (FQR) H. influenzae (HI) Continue to be Infrequently Isolated, Within Worldwide Surveillance Networks (1997-2008), Lead author: Biedenbach DJ, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Linezolid Experience and Accurate Determination of Resistance (LEADER) Program: United States (USA) Results for 2009, Lead author: Ross JE, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Prevalence and Antimicrobial Susceptibility Profile of ESBL- and KPC-producing Enterobacteriaceae in the United States (2003-2008), Lead author: Jones RN, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Assessment of NXL104 Disk Content to Be Used to Test Ceftaroline in Combination, Lead author: Sader HS, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Evaluation of the Effects of pH, Serum Protein Concentration, Media Supplements, Inoculum Size, Media Type, and Incubation Conditions on Activity of Ceftaroline Combined with NXL104, Lead author: Rhomberg PR, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

A Multi-Site Study of the Sensititre® Susceptibility System Compared with the CLSI Microdilution Method using New CLSI Breakpoints for MIC Determination of Enterobacteriaceae vs. Cephems, Lead author: Holliday, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Design and Evaluation of a Novel Dual-target Real-time PCR Assay for Neisseria gonorrhoeae Detection in Clinical Specimens, Lead author: Rebbapragada, presented at 110th annual American Society for Microbiology General Meeting (ASM), May 23 – 27, 2010, San Diego, CA

Telavancin Activity against Gram-positive Bacteria Isolated from Respiratory Tract Specimens of Patients with Nosocomial Pneumonia (2007-2008), Lead author: Mendes RE, presented at American Thoracic Society (ATS), May 14 – 19, 2010, New Orleans, LA

Ceftaroline Activity Against Bacterial Isolates from Patients with Community-Acquired Respiratory Tract Infections from United States Medical Centers in 2009, Including Methicillin-Resistant Staphylococcus aureus, Lead author: Sader HS, presented at American Thoracic Society (ATS), May 14 – 19, 2010, New Orleans, LA

Antimicrobial Activity and Spectrum of the Novel Cephalosporin Ceftaroline Tested Against Bacterial Isolates Causing Skin and Skin Structure Infections in USA Medical Centers, Lead author: Farrell DJ, presented at 30th annual Surgical Infection Society (SIS), April 17 – 20, 2010, Las Vegas, NV

Ceftaroline Activity against Clinical Isolates of Staphylococcus aureus, Including Methicillin-Resistant Strains (MRSA), from United States Hospitals, Lead author: Sader HS, presented at 30th annual Surgical Infection Society (SIS), April 17 – 20, 2010, Las Vegas, NV

Spectrum of activity of ceftaroline/NXL104 and beta-lactam comparator agents tested against methicillin-resistant Staphylococcus aureus carrying different SCCmec types and Gram-negative bacilli with well-characterized resistance mechanisms, Lead author: Castanheira M, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Potent activity of ceftazidime/NXL104 tested against Enterobacteriaceae isolates carrying multiple beta-lactamase enzymes, Lead author: Castanheira M, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial activity of ceftaroline combined with NXL104 tested against a collection of organisms expressing multiple beta-lactamases, Lead author: Farrell DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial activity of tigecycline and comparator agents tested against clinical bacterial strains from the Asia-Pacific region, 2008-2009, Lead author: Jan Bell, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Multicentre evaluation of tigecycline activity in Europe: report from the SENTRY Antimicrobial Surveillance Programme, 2009, Lead author: Farrell DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Daptomycin activity and spectrum when tested against contemporary (2009) Gram-positive strains collected in European medical centres, Lead author: Sader HS, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial susceptibility of daptomycin and comparator agents tested against bloodstream isolates of Staphylococcus aureus: analysis of a 5-year trend in European medical centres (2005-2009), Lead author: Biedenbach DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Eight-year (2002-2009) summary of the Zyvox Annual Appraisal of Potency and Spectrum Programme in European countries, Lead author: Ross JE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Report of linezolid resistance from the Zyvox® Annual Appraisal of Potency and Spectrum Programme (Europe, Latin America, Asia-Pacific), Lead author: Ross JE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial activity of doripenem against clinical bacterial pathogens from Europe, 2009, Lead author: Farrell DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Ceftobiprole activity when tested against clinical bacterial pathogens from Europe, 2009, Lead author: Farrell DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

In vitro activity of ceftaroline tested against leading Gram-positive and -negative European bacterial pathogens collected in 2009, Lead author: Castanheira M, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Activity of ceftaroline against recent (2009) and multidrug-resistant Streptococcus pneumoniae isolates from Europe and the United States, Lead author: Farrell DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Oritavancin activity against Gram-positive pathogens isolated from United States and European medical centres, 2008-2009, Lead author: Mendes RE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Spectrum of activity of oritavancin and comparison agents tested against contemporary Staphylococcus aureus collected in European hospitals, Lead author: Mendes RE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Tigecycline activity tested against infrequently recovered clinical species of non-enteric Gram-negative bacilli, Lead author: Mendes RE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

CEM-101, a novel fluoroketolide, tested against European clinical isolates from 2009 (first-year surveillance results), Lead author: Castanheira M, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Expanded studies of CEM-101, a novel fluoroketolide, tested against invasive isolates of N. meningitidis,including fluoroquinolone-non-susceptible resistant strains, Lead author: Biedenbach DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial activity of the investigational pleuromutilin compound BC-3781 against Gram-positive organisms commonly associated with cutaneous infections, Lead author: Sader HS, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Activity of BC-3205 when tested against Gram-positive organisms responsible from skin and skin structure infections, Lead author: Sader HS, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Disc diffusion and MIC quality control ranges for BC-3205, a novel pleuromutilin class antimicrobial, Lead author: Ross JE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Correlation of in vitro susceptibility testing results for an investigational pleuromutilin (BC-3781) using MIC and disc diffusion methods against Gram-positive pathogens, Lead author: Biedenbach DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Correlations of broth microdilution MIC and disc diffusion results for an investigational agent, BC-3205 among potentially indicated species, Lead author: Biedenbach DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

CEM-102 (fusidic acid) in vitro activity and evaluation of molecular resistance mechanisms among European Gram-positive isolates, 2008-2009, Lead author: Castanheira M, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial activity of ceftaroline tested against Staphylococcus aureus from the United States and Europe, 2008-2009, Lead author: Sader HS, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Antimicrobial spectrum of activity of telavancin and comparator agents tested against methicillin-resistant Staphylococcus aureus recovered from United States and European hospitals over a 3-year sampling period (2007-2009), Lead author: Mendes RE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Activity of ceftaroline against selected clinical isolates of Staphylococcus aureus from the Canadian Bacterial Sentinel Network, Lead author: Farrell DJ, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Spectrum of activity of oritavancin and comparator agents tested against subsets of vancomycin-resistant enterococci from the United States and Europe, Lead author: Mendes RE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Differences between adult and paediatric serotypes and activity of ceftaroline for recent US isolates of Streptococcus pneumoniae, Lead author: Jacobs, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

16S rRNA methylase containing Enterobacteriaceae in the SENTRY Asia-Pacific region frequently harbour plasmid-mediated quinolone resistance and CTX-M types, Lead author: Bell JM, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Initial MIC and disc diffusion quality control ranges for BC-3781 using the CLSI Multi-Laboratory M23-A3 study design, Lead author: Ross JE, presented at 20th annual European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), April 10 – 13, 2010, Vienna, Austria

Five-Year Trend of Antimicrobial Susceptibility Rates and Daptomycin Activity among Staphylococcus aureus Isolates Collected in Latin American Medical Centers (2005-2009), Lead author: Sader HS, presented at 14th annual International Congress on Infectious Diseases (ICID), March 9 – 12, 2010, Miami, FL

Multicenter evaluation of tigecycline activity in Latin America: Report from the SENTRY antimicrobial surveillance program (2009), Lead author: Farrell DJ, presented at 14th annual International Congress on Infectious Diseases (ICID), March 9 – 12, 2010, Miami, FL

Daptomycin activity and spectrum when tested against contemporary (2009) Gram-positive strains collected in Latin American medical centers, Lead author: Sader HS, presented at 14th annual International Congress on Infectious Diseases (ICID), March 9 – 12, 2010, Miami, FL

Daptomycin activity against enterococci from Latin American medical centers, including Vancomycin-resistant strains (2005-2009), Lead author: Sader HS, presented at 14th annual International Congress on Infectious Diseases (ICID), March 9 – 12, 2010, Miami, FL

Tigecycline activity against multidrug-resistant enterobacteriaceae isolated in the Latin American (LA) Region, Lead author: Sader HS, presented at 14th annual International Congress on Infectious Diseases (ICID), March 9 – 12, 2010, Miami, FL

Activity of tigecycline and comparators tested against Streptococcus pneumoniae isolated from patients with community-acquired respiratory tract infection (CARTI) in Latin American medical centers (2005-2009), Lead author: Sader HS, presented at 14th annual International Congress on Infectious Diseases (ICID), March 9 – 12, 2010, Miami, FL

Wild-type MIC distributions and epidemiologic cutoff values for the Echinocandins and Candida spp. by Pfaller MA, Boyken L, Hollis RJ, Kroeger J, Messer SA, Tendolkar S, Jones RN, Turnidge J and Diekema D published in J. Clin. Microbiol. 2010; 48 (1):52-56

Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States by Jacobs MR, Good CE, Windau AR, Bajaksouzian S, Biek D, Critchley I, Sader HS and Jones RN published in Antimicrob. Agents Chemother. 2010; 54 (6): 2716-2719