Publications

Geographic Variations in the Activity of Doripenem and Other Broad-Spectrum Agents: Results from an International Surveillance Program (2003-2005), Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

A Multi-Site Comparison Study of the Sensititre Automated/Manual Susceptibility Plate to the CLSI Microdilution Method for Streptococcus spp. vs. Daptomycin, Lead author: Miskov AM, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Re-Evaluation of Clinical and Laboratory Standards Institute (CLSI) Disk Diffusion Breakpoints for Tetracycline and Doxycycline When Testing Enterobacteriaceae, Lead author: Sader HS, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Recommended Ulifloxacin MIC Quality Control Ranges Using a CLSI Multi-Laboratory M23-A2 Study Design, Lead author: Biedenbach DJ, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

An Assessment of the Sensititre Automated/Manual Susceptibility Plate in Detection of Vancomycin Non-Susceptible Staphylococcus spp., Lead author: Killian SB, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Vancomycin Hetero-resistance has a Small but Significant Effect on the Daptomycin Minimum Inhibitory Concentration of Staphylococcus aureus, Lead author: Bell JM, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Spectrum and Potency of Ceftobiprole Tested Against Staphylococci and Streptococci Recovered from Patients in Latin America (2003-2005), Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In Vitro Activity of Ceftobiprole Tested Against a Recent Collection of North American Pseudomonas aeruginosa, Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Evaluation of the Bactericidal Activity of the Novel Cephalosporin Ceftaroline (PPI-0903M) Compared to Ceftriaxone against Streptococcus pneumoniae, Lead author: Sader HS, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Activity of Doripenem Tested Against an International Collection of ESBL- and AmpC-Producing Enterobacteriaceae, Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Antimicrobial Activities of Doripenem and Other Carbapenems Tested Against Pseudomonas aeruginosa, Other Non-Fermentative Bacilli and Aeromonas spp., Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In Vitro Activity of Daptomycin in Combination with Gentamicin against Contemporary Clinical Isolates of Staphylococcus aureus and Enterococci, Lead author: Sader HS, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In vitro Activity of Dalbavancin Susceptibility Tested Against Staphylococcus spp. and &#223-haemolytic Streptococcus spp. isolated in USA Medical Centers, Lead author: Biedenbach DJ, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Activity of Tigecycline (TIG) Tested Against Recent Acinetobacter spp. Isolates in North American (NA) Hospitals, Lead author: Sader HS, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Activity of Tigecycline Tested against Vancomycin-Resistant Enterococcus faecium Isolated in North America (NA) and Europe (EU), Including Clonal Complex-17 (CC-17) Strains, Lead author: Jones RN, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Evaluation of Colistin Alone or in Combination with Antimicrobial Agents Against Clinical Isolates of Carbapenem-Resistant P. aeruginosa (CR-PSA), Lead author: Chin JN, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Longitudinal Evaluation of Linezolid Activity: Results from the Zyvox Annual Appraisal of Potency and Spectrum (ZAAPS) Surveillance Program (2002-2005), Lead author: Ross JE, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In Vitro Activity of Omiganan Pentahydrochloride Tested Against Vancomycin (VAN) Tolerant, Intermediate (VISA and hVISA) and Resistant (VRSA) S. aureus, Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In vitro Activity of a 2′-Substituted-6-alkylidenepenicillin Sulfone (LN-1-255) as a &#223-Lactamase Inhibitor, Lead author: Buynak JD, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Spectrum and Activity of 2′-Substituted-6-alkylidenepenicillin Sulfone/&#223-lactam Combinations Screened Against Resistant Gram-Negative Bacilli, Lead author: Buynak JD, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Potency and Spectrum of DC-159a Tested Against More Than 800 Recent Clinical Isolates, Lead author: Jones RN, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

DC-159a, a Novel Oral Quinolone, Activity Tested Against Community-Acquired Respiratory Tract (CA-RTI) Pathogens, Lead author: Jones RN, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Comparative In Vitro Activity of DC-159a, a New Oral Fluoroquinolone, Against Viridans Streptococci, Lead author: Smith K, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In Vitro Activity of Nine Developmental Cationic Steroid Compounds (Ceragenins) Against Clinical Isolates of Clostridium difficile, Lead author: Fritsche TR, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

In Vitro Activity of DX-619 Compared to Other Agents against Viridans Streptococci, Lead author: Smith K, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Pneumococcal Conjugate Vaccine Effect on S. pneumoniae Serotype Carriage and Multidrug-Resistance in the United States, Lead author: Mera RM, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Antimicrobial Activity of Tigecycline (TIG) Tested Against Serine Carbapenemase-Producing Enterobacteriaceae Isolated in the United States, Lead author: Sader HS, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Molecular and Epidemiologic Characterization of Community-Associated Methicillin-Resistant S. aureus (CA-MRSA) Isolated from North American Medical Centers: Report from The SENTRY Program (2000- 2004), Lead author: Deshpande LM, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Molecular Characterization of S. aureus (SA) Isolates from a Contemporary (2005) Clinical Trial of Uncomplicated Skin and Skin Structure Infections (uSSSI), Lead author: Jones RN, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Antimicrobial Activity of Tigecycline against Community-Acquired Methicillin-Resistant S. aureus (CA-MRSA) Isolated in North American Medical Centers, Lead author: Jones RN, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Time to Sign and Symptom (S&S) Resolution May Not Differ Between Bacterially and Non-Bacterially Infected Patients with Acute Maxillary Sinusitis (AMS), Lead author: Ambrose PG, presented at 46th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 27 – 30, 2006, San Francisco, California

Potency and Spectrum of Garenoxacin Tested Against an International Collection of Skin and Soft Tissue Infection Pathogens: Report from the SENTRY Antimicrobial Surveillance Program (1999-2004), Lead author: Fritsche TR, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Antimicrobial Activity of Garenoxacin (GRN), a Novel Des-F(6) Quinolone Tested Against 29,460 Community-Acquired Respiratory Pathogens (CA-RTI) from Europe, North America and Latin America, Lead author: Jones RN, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Uniformly Enhanced Activity of Doripenem Compared to Other Carbapenems (Imipenem, Meropenem) When Testing P. aeruginosa Isolates: Results from Three Continents, Lead author: Jones RN, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Comparative In Vitro Activity of Ceftobiprole Against Staphylococcus aureus and Streptococcus pneumoniae: Results From an International Surveillance Programme (2003-2005), Lead author: Fritsche TR, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Use of In Vitro Susceptibility and Pathogen Prevalence Data to Model the Expected Clinical Success Rates of Tigecycline and Other Commonly Used Antimicrobials for Empiric Treatment of Complicated Skin and Skin Structure Infections (cSSSI) in France, Germany and Italy, Lead author: Sader HS, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Surrogate Glycopeptide Testing Used to Predict Susceptibility to Dalbavancin: A Novel Glycolipopeptide, Lead author: Jones RN, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Antimicrobial Activity of Daptomycin Tested Against Staphylococcus aureus and Enterococcus spp. Clinical Strains Isolated in European Medical Centers (2002-2005), Lead author: Sader HS, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Tigecycline Activity Tested Against Gram-positive Cocci and Enterobacteriaceae Collected in Europe, North America and Latin America, Lead author: Sader HS, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Activity of Meclocycline Sulfosalicylate Tested Against Oral Pathogens, Lead author: Jones RN, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Regional Differences in Activity of Tigecycline Tested Against Acinetobacter spp.: Results from a Global Surveillance Programme (2003-2005), Lead author: Fritsche TR, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Tigecycline Activity Against Staphylococcus aureus, Including Vancomycin-Intermediate and -Resistant Isolates, Lead author: Fritsche TR, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Antimicrobial Activity of Tigecycline and Other Broad-Spectrum Agents Tested Against Bloodstream Infection Isolates Collected in France, Germany, and Italy, Lead author: Sader HS, presented at 12th annual International Congress on Infectious Diseases (ICID), June 15 – 18, 2006, Lisbon, Portugal

Carbapenem -Resistant Serratia marcescens Producing SME-2, a Carbapenem-Hydrolyzing Class A β-Lactamase, Isolated in Houston, Texas: Report from the SENTRY Antimicrobial Surveillance Program (2004), Lead author: Sader HS, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida

Re-Emergence of Linezolid Resistance in Clonally Distinct Staphylococcus aureus Strains Causing Pulmonary Infection in a Cystic Fibrosis Patient: Initial Case Studies from Latin America, Lead author: Deshpande LM, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida

Report from the 2005 MYSTIC Surveillance Program (USA): Influence of Antimicrobial Resistant Clusters on Overall Prevalence Patterns, Lead author: Rhomberg PR, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida

A Multi-Site Study of Gemifloxacin MIC Results on the Sensititre® 18-24 Hour Automated/Manual Susceptibility Plate to the CLSI Broth Microdilution Method, Lead author: Miskov AM, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida

A Multi-Site Study of Ertapenem MIC Results on the Sensititre® 18-24 hour Automated/Manual Susceptibility Plate to the CLSI Broth Microdilution Method, Lead author: Killian SB, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida

Multicenter Studies to Establish Tigecycline Disk Diffusion Susceptibility Breakpoints when Testing Acinetobacter spp, Lead author: Jones RN, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida

Assessment of Colistin and Polymyxin B Antimicrobial Susceptibility Testing Methods Against Non-Fermentative Gram-Negative Bacilli (NFGNB), Lead author: Sader HS, presented at 106th annual American Society for Microbiology General Meeting (ASM), May 21 – 25, 2006, Orlando, Florida