JMI LABS IS NOW PART OF LEARN MORE

RmtD 16S RNA methylase in epidemiologically unrelated SPM-1-producing Pseudomonas aeruginosa isolates from Brazil.

RmtD 16S RNA methylase in epidemiologically unrelated SPM-1-producing Pseudomonas aeruginosa isolates from Brazil. by Castanheira M, Fritsche TR, Sader HS and Jones RN published in Antimicrob. Agents Chemother. 2008; 52 (4): 1587-1588

Rapid emergence of blaCTX-M among Enterobacteriaceae in U.S. medical centers: Molecular evaluation from the MYSTIC Program (2007).

Rapid emergence of blaCTX-M among Enterobacteriaceae in U.S. medical centers: Molecular evaluation from the MYSTIC Program (2007). by Castanheira M, Mendes RE, Rhomberg PR and Jones RN published in Microb. Drug Resist. 2008; 14 (3): 211-216

Antimicrobial susceptibility of Gram-negative bacilli isolated in Brazilian hospitals participating in the SENTRY Program (2003-2008).

Antimicrobial susceptibility of Gram-negative bacilli isolated in Brazilian hospitals participating in the SENTRY Program (2003-2008). by Andrade S, Sader HS, Barth A, Ribeiro J, Zoccoli C, Pignatari AC and Gales AC published in Braz. J. Infect. Dis. 2008; 12 (Suppl. 2): S3-S9

Update of the activity of cefditoren and comparator oral ß-lactam agents tested against community-acquired Streptococcus pneumoniae isolates (USA, 2004-2006).

Update of the activity of cefditoren and comparator oral ß-lactam agents tested against community-acquired Streptococcus pneumoniae isolates (USA, 2004-2006). by Fritsche TR, Biedenbach DJ, and Jones RN published in J. Chemother. 2008; 20 (2): 170-174

Evaluation of daptomycin, telavancin, teicoplanin and vancomycin activity in the presence of albumin or serum.

Evaluation of daptomycin, telavancin, teicoplanin and vancomycin activity in the presence of albumin or serum. by Tsuji BT, Leonard SN, Rhomberg PR and Rybak MJ published in Microbiol. Infect. Dis. 2008; 60 (4): 441-444

Activity of daptomycin and selected antimicrobial agents tested against Staphylococcus aureus from patients with bloodstream infections hospitalized in European medical centers.

Activity of daptomycin and selected antimicrobial agents tested against Staphylococcus aureus from patients with bloodstream infections hospitalized in European medical centers. by Sader HS, Watters AA, Fritsche TR and Jones RN published in J. Chemother. 2008; 20 (1): 28-32

Antimicrobial activity of tigecycline against community-acquired methicillin-resistant Staphylococcus aureus isolates recovered from North American medical centers.

Antimicrobial activity of tigecycline against community-acquired methicillin-resistant Staphylococcus aureus isolates recovered from North American medical centers. by Mendes RE, Sader HS, Deshpande L and Jones RN published in Diagn. Microbiol. Infect. Dis. 2008; 60 (4): 433-436

Pharmacokinetic and pharmacodynamic profile of ceftobiprole.

Pharmacokinetic and pharmacodynamic profile of ceftobiprole. by Lodise TP, Patel N, Renaud-Mutart A, Gorodecky E, Fritsche TR and Jones RN published in Diagn. Microbiol. Infect. Dis. 2008; 61 (1): 96-102

Frequency of occurrence and daptomycin susceptibility rates of Gram-positive organisms causing bloodstream infections in cancer patients.

Frequency of occurrence and daptomycin susceptibility rates of Gram-positive organisms causing bloodstream infections in cancer patients. by Sader HS, Fritsche TR and Jones RN published in J. Chemother. 2008; 20 (5): 570-576

Metallo-beta-lactamase IMP-18 is located in a class 1 integron (In96) in a clinical isolate of Pseudomonas aeruginosa from Mexico.

Metallo-beta-lactamase IMP-18 is located in a class 1 integron (In96) in a clinical isolate of Pseudomonas aeruginosa from Mexico. by Garza-Ramos U, Tinoco P, Silva-Sanchez J, Morfin-Otero R, Rodriquez-Noriega E, Leon-Garnica G, Sader HS and Jones RN published in Int. J. Antimicrob. Agents 2008; 31 (1): 78-80.

Prevalence and genetic characterization of blaCTX-M among Klebsiella pneumoniae isolates collected in an intensive care unit in Brazil.

Prevalence and genetic characterization of blaCTX-M among Klebsiella pneumoniae isolates collected in an intensive care unit in Brazil. by Do Carmo Filho JR, Silva RM, Castanheira M, Tognim MCB, Gales AC and Sader HS published in J. Chemother. 2008; 20 (5): 600-603

Antimicrobial activity of ceftobiprole, a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, tested against contemporary pathogens: Results from the SENTRY Antimicrobial Surveillance Program (2005-2006).

Antimicrobial activity of ceftobiprole, a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, tested against contemporary pathogens: Results from the SENTRY Antimicrobial Surveillance Program (2005-2006). by Fritsche TR, Sader HS and Jones RN published in Diagn. Microbiol. Infect. Dis. 2008; 61 (1): 86-95

Antimicrobial activity of cefditoren tested against contemporary (2004-2006) isolates of Haemophilus influenzae and Moraxella catarrhalis responsible for community-acquired respiratory tract infections in the United States.

Antimicrobial activity of cefditoren tested against contemporary (2004-2006) isolates of Haemophilus influenzae and Moraxella catarrhalis responsible for community-acquired respiratory tract infections in the United States. by Biedenbach DJ, Jones RN and Fritsche TR published in Diagn. Microbiol. Infect. Dis. 2008; 61 (2): 240-244

Comparative activity of meropenem in US medical centers (2007): Initiating the 2nd decade of MYSTIC Program surveillance.

Comparative activity of meropenem in US medical centers (2007): Initiating the 2nd decade of MYSTIC Program surveillance. by Jones RN, Kirby JT and Rhomberg PR published in Diagn. Microbiol. Infect. Dis. 2008; 61 (2):203-213

Antimicrobial activity of omiganan pentahydrochloride tested against contemporary bacterial pathogens commonly responsible for catheter-associated infections.

Antimicrobial activity of omiganan pentahydrochloride tested against contemporary bacterial pathogens commonly responsible for catheter-associated infections. by Fritsche TR, Rhomberg PR, Sader HS and Jones RN published in J. Antimicrob. Chemother. 2008; 61 (5): 1092-1098

In vitro activity of omiganan pentahydrochloride tested against vancomycin-tolerant, -intermediate and -resistant Staphylococcus aureus.

In vitro activity of omiganan pentahydrochloride tested against vancomycin-tolerant, -intermediate and -resistant Staphylococcus aureus. by Fritsche TR, Rhomberg PR, Sader HS and Jones RN published in Diagn. Microbiol. Infect. Dis. 2008; 60 (4): 399-403

Antimicrobial activities of tigecycline and other broad spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: Report from the SENTRY Antimicrobial Surveillance Program.

Antimicrobial activities of tigecycline and other broad spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase-producing Enterobacteriaceae: Report from the SENTRY Antimicrobial Surveillance Program. by Castanheira M, Sader HS, Deshpande LM, Fritsche TR and Jones RN published in Antimicrob. Agents Chemother. 2008; 52 (2): 570-573

Novel ß-lactams.

Novel ß-lactams. by Gales AC and Sader HS published in Braz. J. Infect. Dis. 2008; 12 (Suppl. 2): S46-S58

Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis.

Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. by Ambrose PG, Anon JB, Bhavnani SM, Okusanya OO, Jones RN, Paglia MR, Kahn J and Drusano GL published in Diagn. Microbiol. Infect. Dis. 2008; 61 (1): 13-20

Update of the in vitro activity of daptomycin tested against 6,710 Gram-positive cocci isolated in North America (2006).

Update of the in vitro activity of daptomycin tested against 6,710 Gram-positive cocci isolated in North America (2006). by Castanheira M, Jones RN and Sader HS published in Diagn. Microbiol. Infect. Dis. 2008; 61 (2): 235-239

IMP-producing Pseudomonas aeruginosa strain isolated in a US medical center: A recent arrival from Mexico.

IMP-producing Pseudomonas aeruginosa strain isolated in a US medical center: A recent arrival from Mexico. by Martin CA, Morita K, Ribes JA, Deshpande LM, Sader HS and Castanheira M published in Antimicrob. Agents Chemother. 2008; 52 (6): 2289-2290

Metallo-ß-lactamase gene blaIMP-15 in class 1 integron, In95, from Pseudomonas aeruginosa isolates from a hospital in Mexico.

Metallo-ß-lactamase gene blaIMP-15 in class 1 integron, In95, from Pseudomonas aeruginosa isolates from a hospital in Mexico. by Garza-Ramos U, Morfin-Otero R, Sader HS, Jones RN, Hernandez E, Rodriguez-Noriega E, Sanchez A, Carrillo B, Esparza-Ahumada S and Silva-Sanchez J published in Antimicrob. Agents Chemother. 2008; 52 (8): 2943-2946

Comparison of Automated and Reference Susceptibility Test Results: Evidence for Bias When Testing Pseudomonas aeruginosa (PSA) Against ß-lactam Agents

Comparison of Automated and Reference Susceptibility Test Results: Evidence for Bias When Testing Pseudomonas aeruginosa (PSA) Against ß-lactam Agents, Lead author: Fritsche TR, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Activity of Daptomycin and Selected Comparators Tested against Staphylococcus aureus Causing Bloodstream Infections (BSI) in Dialysis Patients

Antimicrobial Activity of Daptomycin and Selected Comparators Tested against Staphylococcus aureus Causing Bloodstream Infections (BSI) in Dialysis Patients, Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

In Vitro Activity of Telavancin Against Gram-positive Pathogens, Including Resistant Subsets: Results from a Global Surveillance Program (2007)

In Vitro Activity of Telavancin Against Gram-positive Pathogens, Including Resistant Subsets: Results from a Global Surveillance Program (2007), Lead author: Fritsche TR, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

In Vitro Activity of Omiganan Pentahydrochloride (OMI) Against >1,600 Clinical Trial Isolates

In Vitro Activity of Omiganan Pentahydrochloride (OMI) Against >1,600 Clinical Trial Isolates, Lead author: Fritsche TR, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Linezolid (LZD) Experience and Accurate Determination of Resistance (LEADER) Program 2006: Emerging Oxazolidinone and Inducible Clindamycin (CC) Resistances (R)

Linezolid (LZD) Experience and Accurate Determination of Resistance (LEADER) Program 2006: Emerging Oxazolidinone and Inducible Clindamycin (CC) Resistances (R), Lead author: Jones RN, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Susceptibility Profiles of Bacterial Isolates from Bloodstream Infections of Transplant Recipient Patients

Antimicrobial Susceptibility Profiles of Bacterial Isolates from Bloodstream Infections of Transplant Recipient Patients, Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Occurrences of ESBL and Other ß-lactamases (BL) Among Enterobacteriaceae (ENT) Isolated in USA Medical Centers: 10-Year Report from the SENTRY Program

Occurrences of ESBL and Other ß-lactamases (BL) Among Enterobacteriaceae (ENT) Isolated in USA Medical Centers: 10-Year Report from the SENTRY Program, Lead author: Jones RN, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Susceptibility of Gram-Positive (GP) Organisms Isolated from North American (NA) Hospitals: Results from the Daptomycin (DAP) Surveillance Program, 2004 – 2006

Antimicrobial Susceptibility of Gram-Positive (GP) Organisms Isolated from North American (NA) Hospitals: Results from the Daptomycin (DAP) Surveillance Program, 2004 – 2006, Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Activity of Daptomycin Tested against Gram-positive Organisms Collected from Hospitalized Patients with Cancer Hospitalized in the United States (USA) Hospitals

Antimicrobial Activity of Daptomycin Tested against Gram-positive Organisms Collected from Hospitalized Patients with Cancer Hospitalized in the United States (USA) Hospitals, Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Assessment of Tigecycline (TGC) and Other Broad-Spectrum Agents Activities Tested Against Enterobacteriaceae (ENT) from the Asia-Pacific Region (2006)

Assessment of Tigecycline (TGC) and Other Broad-Spectrum Agents Activities Tested Against Enterobacteriaceae (ENT) from the Asia-Pacific Region (2006), Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Activity of Tigecycline and Comparator Agents Tested Against Gram-Positive (GP) Organisms Collected in the Asia-Pacific Region in 2006

Antimicrobial Activity of Tigecycline and Comparator Agents Tested Against Gram-Positive (GP) Organisms Collected in the Asia-Pacific Region in 2006, Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Tigecycline: An Active Antimicrobial Agent against Multidrug-Resistant Acinetobacter spp. Isolated in Latin America

Tigecycline: An Active Antimicrobial Agent against Multidrug-Resistant Acinetobacter spp. Isolated in Latin America, Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Evaluation of Cefditoren (CDN) and Comparator Oral &#223-lactam Agents Tested Against Recent Community-Acquired Streptococcus pneumoniae (USA; 2004-2006)

Evaluation of Cefditoren (CDN) and Comparator Oral &#223-lactam Agents Tested Against Recent Community-Acquired Streptococcus pneumoniae (USA; 2004-2006), Lead author: Fritsche TR, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Potency of Omiganan Pentahydrochloride (OMI): Evidence for Retained or Enhanced Activity When Formulated in a Gel Matrix

Potency of Omiganan Pentahydrochloride (OMI): Evidence for Retained or Enhanced Activity When Formulated in a Gel Matrix, Lead author: Fritsche TR, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Activity of Cefditoren (CDN) Tested Against Haemophilus influenzae (HI) and Moraxella catarrhalis (MCAT) Causing Community-Acquired Respiratory Tract Infections (USA; 2004-2006)

Antimicrobial Activity of Cefditoren (CDN) Tested Against Haemophilus influenzae (HI) and Moraxella catarrhalis (MCAT) Causing Community-Acquired Respiratory Tract Infections (USA; 2004-2006), Lead author: Fritsche TR, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Quinolone Resistant Escherichia coli at a Cancer Center

Quinolone Resistant Escherichia coli at a Cancer Center, Lead author: Rolston KV, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Evaluation of Susceptibility Patterns of Klebsiella spp. Isolated in Latin America. Results of the SENTRY Antimicrobial Surveillance Program (1997-2006)

Evaluation of Susceptibility Patterns of Klebsiella spp. Isolated in Latin America. Results of the SENTRY Antimicrobial Surveillance Program (1997-2006), Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Antimicrobial Susceptibility of Pseudomonas aeruginosa (PSA) Causing Bloodstream Infections (BSI) in Brazilian Medical Centers: Results of the SENTRY Antimicrobial Surveillance Program (2001-2006)

Antimicrobial Susceptibility of Pseudomonas aeruginosa (PSA) Causing Bloodstream Infections (BSI) in Brazilian Medical Centers: Results of the SENTRY Antimicrobial Surveillance Program (2001-2006), Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Metallo-&#223-Lactamases Genes, blaIMP-15 and blaIMP-18 in a Class 1 Integrons form Pseudomonas aeruginosa Clinical Isolates from a Hospital in Mexico

Metallo-&#223-Lactamases Genes, blaIMP-15 and blaIMP-18 in a Class 1 Integrons form Pseudomonas aeruginosa Clinical Isolates from a Hospital in Mexico, Lead author: Garza-Ramos U, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Spectrum and Potency of Tigecycline Tested Against Non-Fermentative Gram-negative Bacilli (NFGN) Collected in Across the Asia-Pacific Region (2006)

Spectrum and Potency of Tigecycline Tested Against Non-Fermentative Gram-negative Bacilli (NFGN) Collected in Across the Asia-Pacific Region (2006), Lead author: Sader HS, presented at 45th annual Infectious Diseases Society of America (IDSA), October 4 – 7, 2007, San Diego, CA

Activity of Tigecycline (TGC) Tested against Clinical Pathogens Collected in Korea, the Philippines, Singapore and Thailand (2006)

Activity of Tigecycline (TGC) Tested against Clinical Pathogens Collected in Korea, the Philippines, Singapore and Thailand (2006), Lead author: Bell JM, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

Antimicrobial Activity of Iclaprim Tested against Recent Staphylococcus aureus Clinical Isolates: Results from the International Study of Iclaprim Susceptility (ISIS)

Antimicrobial Activity of Iclaprim Tested against Recent Staphylococcus aureus Clinical Isolates: Results from the International Study of Iclaprim Susceptility (ISIS), Lead author: Sader HS, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

In Vitro Activity of Iclaprim and Comparison Agents Tested against Neisseria gonorrhoeae Including Growth Stimulating Effects

In Vitro Activity of Iclaprim and Comparison Agents Tested against Neisseria gonorrhoeae Including Growth Stimulating Effects, Lead author: Sader HS, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

Antimicrobial Activity of a Novel Dihydrofolate Reductase, Iclaprim, Tested against Clinical Strains of Enterobacteriaceae (ENT): Results from the International Study of Iclaprim Susceptibility (ISIS)

Antimicrobial Activity of a Novel Dihydrofolate Reductase, Iclaprim, Tested against Clinical Strains of Enterobacteriaceae (ENT): Results from the International Study of Iclaprim Susceptibility (ISIS), Lead author: Sader HS, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

Comparative Evaluation of Iclaprim Potency and Bactericidal Activity Tested against Enterococci: Results from the International Study of Iclaprim Susceptibility (ISIS)

Comparative Evaluation of Iclaprim Potency and Bactericidal Activity Tested against Enterococci: Results from the International Study of Iclaprim Susceptibility (ISIS), Lead author: Sader HS, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

In Vitro Activity of Iclaprim, a Novel Diaminopyrimidine, Tested against &#223-Haemolytic Streptococci from the U.S. and Europe: Results from the International Study of Iclaprim Susceptibility (ISIS).

In Vitro Activity of Iclaprim, a Novel Diaminopyrimidine, Tested against &#223-Haemolytic Streptococci from the U.S. and Europe: Results from the International Study of Iclaprim Susceptibility (ISIS)., Lead author: Sader HS, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

Evaluation of the Novel Ceragenin, CSA-13 Activity and Potential Synergy (SYN) against Clinical Isolates of Pseudomonas aeruginosa (PA), Including Multi-Drug Resistant PA (MDR-PA)

Evaluation of the Novel Ceragenin, CSA-13 Activity and Potential Synergy (SYN) against Clinical Isolates of Pseudomonas aeruginosa (PA), Including Multi-Drug Resistant PA (MDR-PA), Lead author: Chin JN, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL

Discovery of EP-014887: A Novel Oxime 3,6-Bicyclolide with High Potency against MRSA and a Favorable In Vivo Efficacy Profile

Discovery of EP-014887: A Novel Oxime 3,6-Bicyclolide with High Potency against MRSA and a Favorable In Vivo Efficacy Profile, Lead author: Tang D, presented at 47th annual Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), September 17 – 20, 2007, Chicago, IL